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Fertiscope

mRNA vaccination (COVID-19)

Messenger RNA vaccine

Evidence level : Established: no confirmed effect on fertility Medication & treatmentsMechanism : Medication burden

🟢 A link with fertility is documented by numerous, converging human studies, endorsed by health authorities.

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In brief

COVID vaccine and fertility: this page reviews mRNA vaccination (COVID-19) (Messenger RNA vaccine) — documented mechanism, everyday exposure situations and possible alternatives. Level of evidence: Established: no confirmed effect on fertility.

Where it's found
COVID-19 vaccination with an mRNA vaccine (Pfizer-BioNTech, Moderna).
Suspected mechanism
Several independent, large-scale cohorts (2026 Swedish study on approximately 60,000 women, Swissmedic analysis, EARTH/Boston University studies, Sheba Medical Center) found no confirmed link with female or male fertility. Transient menstrual cycle disturbances after vaccination have been documented and studied by the NIH (US National Institutes of Health), with no demonstrated medium-term effect on fertility.
Suggested alternative
No action is needed based on currently available data; pharmacovigilance monitoring remains active.
Source
Linköping University 2026; Swissmedic; EARTH studies (Boston University); Sheba Medical Center; NIH.

Frequently asked questions

mRNA vaccination (COVID-19): how is it linked to infertility?

Several independent, large-scale cohorts (2026 Swedish study on approximately 60,000 women, Swissmedic analysis, EARTH/Boston University studies, Sheba Medical Center) found no confirmed link with female or male fertility. Transient menstrual cycle disturbances after vaccination have been documented and studied by the NIH (US National Institutes of Health), with no demonstrated medium-term effect on fertility.

Where is mRNA vaccination (COVID-19) found in everyday life?

COVID-19 vaccination with an mRNA vaccine (Pfizer-BioNTech, Moderna).

How can exposure to mRNA vaccination (COVID-19) be reduced?

No action is needed based on currently available data; pharmacovigilance monitoring remains active.

What is the level of evidence for mRNA vaccination (COVID-19)?

Established: no confirmed effect on fertility. A link with fertility is documented by numerous, converging human studies, endorsed by health authorities.

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Related factors

Including a factor does not mean it causes infertility: it is simply worth monitoring, depending on its level of evidence.

Content last updated: September 14, 2026