Non-steroidal anti-inflammatory drugs (NSAIDs)
NSAIDs
Evidence level : Probable Medication & treatmentsMechanism : Medication burden
🟡 Several human studies point the same way, with a plausible biological mechanism, but the evidence is not yet conclusive.
- Where it's found
- Ibuprofen, ketoprofen, high-dose aspirin, often self-medicated.
- Suspected mechanism
- Inhibition of prostaglandins, which are involved in ovulation and implantation; prolonged, high-dose use is associated with anovulatory cycles.
- Suggested alternative
- Reserve NSAIDs for short episodes and ask a pharmacist for advice in case of regular use.
- Source
- ANSM (French medicines agency), NSAID warnings; studies on anovulation.
Map your everyday exposures in about ten minutes.
Take the questionnaireRelated factors
Including a factor does not mean it causes infertility: it is simply worth monitoring, depending on its level of evidence.
Content last updated: September 14, 2026