Prior chemotherapy or radiotherapy
Oncology treatments
Evidence level : Established Medication & treatmentsMechanism : Medication burden
🟢 A link with fertility is documented by numerous, converging human studies, endorsed by health authorities.
- Where it's found
- History of cancer treatment, especially before age 40.
- Suspected mechanism
- Direct and sometimes lasting toxicity on oocytes and sperm-producing cells, depending on the doses received.
- Suggested alternative
- A specialized fertility assessment is warranted; gamete preservation is provided for by law in France.
- Source
- INCa (French national cancer institute), fertility preservation; ASCO guidelines.
Map your everyday exposures in about ten minutes.
Take the questionnaireRelated factors
Including a factor does not mean it causes infertility: it is simply worth monitoring, depending on its level of evidence.
Content last updated: September 14, 2026